The Best Anti-Anxiety Supplements (2021 Reviews)


In today’s busy, race-to-the-finish, can’t-stop-won’t-stop society, more and more people find themselves suffering from anxiety and high stress. The truth of the matter is, it’s easy to succumb and nearly impossible to avoid, especially when faced with enough everyday responsibilities to fill a 27-hour day. If only we could slow our planet’s rotation…

But we can’t. And so, you’ve probably found yourself, at least occasionally, facing common anxiety symptoms: a racing mind, regular overanalyzing and overthinking, having trouble focusing, and just generally feeling like you have too much on your plate. While it can help to remember that you really do have more on your plate than is preferable, this presence-of-mind doesn’t mitigate an overarching sense of dread and overwhelm. You are constantly forced to multitask, to juggle your responsibilities, and to do it all with a smile.

Under such stressors, it is thought that 15 million Americans suffer, in some way, from some form of anxiety; approximately 2/3 of those sufferers seek some sort of treatment. Anxiety causes everything from mental fatigue to physical exhaustion, with every sort of debilitating effect in between. Anxiety wears on your body and your emotions.

And so, in a culture with ever-increasing responsibilities and ever-growing stress, it’s no surprise that people have turned to homeopathic and natural anxiety-relievers. Of course, that means that there are dozens, if not hundreds of stress and anxiety supplements on the market today. It’s hard to know which are natural, which work best, and which employ the ingredients you need, for your most common symptoms.

Note: Before taking a homeopathic or natural anxiety-relief supplement, please speak with your healthcare provider. It’s important to discuss your symptoms and possible treatments, as well as to understand any interactions between natural ingredients and other medications you may take.

10 Best Natural Supplements for Anxiety (Sort-able Chart)

Zahler CalmEase Natural Essences Calming Support4.0 stars
BeCalm Premium Stress & Anxiety Relief Supplement4.3 stars
NutriSuppz Anti Anxiety Formula3.8 stars
True Veda Organic Ashwagandha4.7 stars
Calm Natural Anti Stress Calming Supplement4.7 stars
Crystal Clear Anxiety Relief and Stress Support SupplementN/A
Ridgecrest Anxiety Free Stress Relief Complex4.3 stars
Nutratech Alprazium – All Natural Stress Relief & Anti-Anxiety Supplement4.3 stars
Vital Fuse Soothe Stress Natural Stress Reliever4.3 stars
Zhou Nutrition Calm Now Soothing Stress Support4.2 stars
*costs are estimated
*ratings are based on Amazon user ratings
*main ingredients are first three listed on package

Buying Information

Natural supplements to relieve anxiety can be very effective, especially from a whole mind-body standpoint: These homeopathic remedies use herbs, amino acids, and vitamins/minerals to not only reduce your stress, but also to supply you with a boost of the energy and concentration needed to tackle your busy schedule – without the anxiety-ridden side effects, thank you very much.

The key to identifying the best anxiety-reliever for you, is in starting with your symptoms: Do you often feel rundown and tired, unable to summon the energy to handle your mountainous to-list? If so, then look for a supplement with B-vitamins, which have been shown to optimize brain function and boost your energy levels.

On the other hand, if you are strung out and so anxious you find it hard to relax, then you may be after a supplement containing the amino acid L-theanine, which can promote the production of alpha brain waves, in turn mimicking the effects of meditation, including increased metal acuity and deep relaxation.

natural supplements for anxiety
Ashwagandha is a powerful and natural anxiety reliever

Other ingredients get to the heart of your stress and anxiety: magnesium, which has been shown to help relieve the symptoms of stress; chamomile to promote calm; valerian root to manage anxiety and promote physical relaxation; and ashwagandha to increase concentration and support a good night’s sleep. Among others.

To make your search easier, we’ve compiled a list of ten of the most natural, most effective anxiety relief supplements on the market today. The following represent all-natural, often proprietary blends of effective, natural ingredients scientifically proven to reduce stress. Most contain only from-the-earth ingredients, and several are certified organic and/or meet special dietary restrictions, including vegan diets. Relieve your anxiety, the natural way – without any of the nasty side effects of common prescription drugs.

Reviews of the Top-Rated Supplements for Anxiety

  1. Zahler CalmEase Natural Essences Calming Support

Zahler’s CalmEase is an advanced anti-stress supplement that offers calm, reduced anxiety, and overall health and wellbeing to boost your mental and physical wellness. Made in the USA, this supplement is manufactured and bottled in a GMP- and NSF-certified facility.

Unlike other products on our list, CalmEase is not a daily pill; instead, this liquid formula offers, in equal parts, a 7x dilution of homeopathic Helianthemum nummularium (common rock-rose), Clematis vitalba (Old Man’s Beard), Impatiens glandulifera (ornamental jewelweed), Prunus cerasifera (cherry plum), and Ornithogalum umbellatum (Star of Bethlehem), among other ingredients.

It’s easy to take a bottle of CalmEase wherever you go, so you can quickly down these fast-acting drops as a tonic to calm anxiety, soothe stress, and strengthen your mental health, no matter where you are. Naturally safe and highly effective, you’ll feel immediate relief from your racing heartbeat, rising stress, and galloping anxiety. And that’s what we call welcome relief.

  1. BeCalm Premium Stress & Anxiety Relief Supplement
BeCalm Premium Stress & Anxiety Relief Supplement

Komplete Balance’s Be Calm formula is an effective, safe, and natural stress-reliever, designed to help reduce your anxiety and stay calm, positive and poised, all while supporting your overall wellbeing and emotional stability.

This natural anxiety-reliever is designed to help you reduce mental and physical fatigue under stressful conditions. The not-so-secret secret is in the powerful and proprietary combination of natural hops flower powder, chamomile flower powder, valerian root powder, passion flower (herb & flower), and an assortment of vitamins. This powerful combination of vitamins, minerals, and herbs have been scientifically proven to reduce stress and give your mind a boost to function.

We love that Be Calm is made in the USA (in a GMP certified facility) and is non-GMO.

  1. NutriSuppz Anti Anxiety Formula

Whether you’re in desperate search of a better mood, increased calm, and more positive vibes, or have bigger problems – social anxiety, panic attacks, anxiety disorder, shortness of breath, depression, paranoia, post-traumatic stress disorder, and similar conditions – NutriSuppz Anti-Anxiety formula may be your key to increased serotonin production, reduced stress, and less anxiety.

To help reduce stress and anxiety, without the common side effects of prescription medications, NutriSuppz Anti-Anxiety is a non-addictive homeopathic anxiety reliever that relies on a proprietary blend of vitamins and minerals, plus a healthy helping of herbs and amino acids, among them gaba, L-theanine, 5-HTP, ashwagandha, magnesium oxide, chamomile, and St. John’s Wort, among other mood boosters and relaxers.

You’ll also appreciate the 100% satisfaction guarantee: If you don’t feel more relaxed and less anxious after taking NutriSuppz Anti-Anxiety, they’ll refund your money – no questions asked.

  1. True Veda Organic Ashwagandha


It doesn’t get much purer than True Veda’s Organic Ashwagandha supplement, which offers certified-organic, gluten-free and incredibly potent ashwagandha extract to help you lead a healthy and stress-free lifestyle.

Ashwaganda, also known as Withania somnifera or Indian Ginsing, is one of nature’s most powerful herbs. Its benefits include stress relief and improved relaxation, but ashwaganda goes beyond, helping boost your immune system, enhance memory, improve concentration, and encourage mental acuity. Additionally, it supports cardiovascular healthy, promotes endurance, and helps build physical strength – the overall wellbeing package, to help you stay healthy and anxiety-free, without prescription medications.

For 14 years, True Veda worked to develop a potent, full-spectrum root extract that is at least three-times more potent than other ashwagandha extracts on the market today. The result, KSM-66®, is a root-only ashwagandha extract that has been clinically proven to aid in stress and anxiety relief. It has also been scientifically shown to improve energy and endurance in athletes. BOOM! This supplement is made in the U.K. and certified pesticide- and chemical-free by the USA.

  1. Calm Natural Anti Stress Calming Supplement

For everyone who lives a busy life, there is CALM: a made-in-the-USA, all-natural, non-GMO supplement with no fillers, no binders, and no artificial ingredients. Produced in a GMP-certified facility, CALM was formulated by a team of medical professionals and designed for today’s busy men and women. The goal: to deliver natural stress- and anxiety-relievers, to allow you to live your best life.

CALM starts with vitamins and minerals proven to help brain function, stabilize mood, and increase your energy levels: magnesium, to help you handle everyday stress; vitamins B-6 and B-12 to optimize brain function and help your energy levels; folic acid, to improve symptoms of depression and anxiety; and chamomile and valerian root, to manage anxiety, promote physical calm, and improve your brain’s reaction times, so you can respond quickly and more efficiently to whatever life hands you.

You’ll appreciate that CALM is based on scientific research and formulated by medical doctors; in other words, the people who best understand anxiety and its effect on your body and brain. The resulting supplement helps you shed your everyday stresses to reach peak performance and maximize your day.

  1. Crystal Clear Anxiety Relief and Stress Support Supplement


Swap your nerves for calm, and your scattered thoughts for focus, with Crystal Clear Anxiety Relief. This anxiety and stress-support supplement is packed full of natural vitamins, herbs, minerals, and amino acids to help relieve the symptoms of everyday stress, social anxiety, and depression. Additional benefits: a boost in focus, improved emotional balance, total relaxation, and better mood.

You’ll appreciate this supplement’s list of professionally formulated and yet totally readable ingredients, which include familiar anxiety relievers like passion flower, chamomile, and lemon balm. Crystal Clear adds to the mix oat straw, magnolia, gaba, ashwagandha, and L-theanine – your key to unlocking your inner calm and successfully tackling all those day-to-day tasks that fill up your plate.

We also love the no-questions-asked guarantee: If you’re not 100% satisfied – if you haven’t experienced noticeably lower levels of stress, anxiety, and melancholy – Crystal Clear will give you your money back. The only thing you have to lose are your unwanted symptoms.

  1. Ridgecrest Anxiety Free Stress Relief Complex


In a fast-paced world, you need a powerful stress-reliever like Anxiety Free. Designed to relieve stress, reduce fatigue, and manage tension, as well as to counteract the negative effects of this unfavorable trifecta, this natural supplement increases calm and encourages your overall well-being and mental health.

Anxiety Free owes its effect to two powerful main ingredients: L-theanine and ashwagandha. L-theanine is an important amino acid that has been linked to the production of alpha brain waves, which help promote the feelings of mental alertness and deep relaxation associated with meditation.

Then there’s the organic ashwagandha extract, standardized to 10% with anolides, which is eight times more potent than the standard ashwagandha on the market. Extracted from both leaves and roots, this extract has been shown to boost your energy and increase concentration and mental acuity, while simultaneously reducing stress, minimizing anxiety, and supporting restful sleep. Ashwagandha also supports healthy cardiovascular function.

  1. Nutratech Alprazium – All Natural Stress Relief & Anti-Anxiety Supplement


Nutratech’s Alprazium is a mood-enhancer and anti-anxiety supplement that safely promotes improved mood, increased relaxation, and reduced anxiety. Additionally, the ingredients in Alprazium help mitigate environmental and psychological stressors, which are growing fast and without stop in today’s fast-paced world.

Alprazium is comprised of a proprietary blend of nine of the most renowned, natural ingredients proven to help with anxiety, depression, stress and mood: Piper methysticum 40% extract, l-theanine, L-tryptophan, gaba, 5-HTP, passion flower extract, California poppy, valerian root, and melatonin.

The goal of Alprazium, as with many natural anxiety relievers, is to slowly build in your system, over time to create an overall effect of a balanced mood, relief of tension, and stress control. It’s safe, affordable, non-habit-forming, and made right here in the USA. Even better, Alprazium comes with a 30-day, money-back satisfaction guarantee, so you can try it at zero risk.

  1. Vital Fuse Soothe Stress Natural Stress Reliever


Calming, not sedating – that is the promise of VitalFuse’s Soothe Stress supplement, a mood booster and anxiety reducer made from Mother Nature’s best remedies. This daily supplement is designed for anyone who wants to take back control of his or her mood, whether you’re suffering from panic, or restlessness, or stress, or other mood imbalances. Reestablish your equilibrium without the side effects.

It starts with the most natural of ingredients – vitamins, minerals, herbs and amino acids, including ashwagandha root powder, L-theanine, glycine, glutamine, valerian root extract, and chamomile extract. The result is a non-habit-forming capsule that provides anxiety relief without the drowsiness, poor concentration, or mental fog. Even better, Soothe Stress actually helps you stay alert throughout your busy day.

What’s more, Soothe Stress is natural not only for what it contains, but what it doesn’t: in this case, that means no artificial or addictive ingredients. It’s made in the USA and if you don’t love your results, Vital Fuse offers a 100% satisfaction, money-back guarantee. In other words, you have nothing to lose.

  1. Zhou Nutrition Calm Now Soothing Stress Support


We all have those days – those mornings when you wake up and feel like you’re already behind on absolutely everything. Well, for those days (and for every other day) there’s Zhou Nutrition’s Calm Now, a natural supplement designed for your busy life and pell-mell pace.

The key to Calm Now is in the expertly crafted, natural formula, which is not only designed to promote calm and relieve anxiety, but also to avoid causing drowsiness. The key is in the carefully curated ingredient list, which includes a proprietary blend based on both Eastern herbal traditions and modern medicine.

Calm Now is comprised of ashwagandha, rhodiola rosea, passion flower, bacopa monnieri, hawthorn berry, lemon balm, and other natural herbs, vitamins, and minerals. They’ll help you stay calm and focused, even on the busiest of days, and will promote an overall sense of positivity, relaxation, and mind-body wellbeing.


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